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High-Purity Mitochondrial Peptide for Canada
SS-31 (also known in scientific literature as Elamipretide) is a synthetic, mitochondria-targeted research peptide that has gained significant attention among Canadian researchers. Unlike most peptides that act on cell surface receptors, SS-31’s unique structure allows it to accumulate rapidly and specifically on the inner mitochondrial membrane (IMM) [1, 2].
Its stability, purity, and predictable behaviour make it a valuable tool in cellular bioenergetics, oxidative stress modelling, and mitochondrial pathway studies. SS-31 is a cornerstone for labs exploring dysfunction related to energy, stress, and structural pathways.
This 2025–2026 guide provides Canadian researchers with:
All details here are strictly for scientific, laboratory, and in-vitro research.
Not for human or animal use.
SS-31 is a small, linear tetrapeptide with the sequence D-Arg-Dmt-Lys-Phe-NH2 [3]. Its structure gives it a net positive charge which is the critical feature that drives its targeting [1.4, 3.3].
The core mechanism of SS-31 is its high-affinity interaction with the phospholipid Cardiolipin (CL).
CL Localization: Cardiolipin is unique because it is almost exclusively found on the Inner Mitochondrial Membrane (IMM) [1.1].
CL Function: CL is essential for organizing the protein complexes of the Electron Transport Chain (ETC) into supercomplexes [1.3]. Oxidative stress can peroxidize (damage) CL, leading to ETC disorganization and increased Reactive Oxygen Species (ROS) production [2.3].
SS-31 Action: SS-31 is hypothesized to stabilize CL structure, preventing its peroxidation and maintaining the optimal organization of the ETC [1.4].
This mechanism allows researchers to study the immediate effects of boosting ATP and bioenergetic signalling frameworks and reducing ROS at the source, rather than just scavenging ROS after it has formed.
Canadian laboratories use SS-31 because:
SS-31 is part of a growing mitochondrial peptide cluster that includes:
This makes it a core peptide for labs exploring energy, stress, and structural pathways.
As with all peptides used in Canadian labs:
Purity matters because mitochondrial research relies heavily on precision and reproducibility.
A compliant COA should list:
Researchers rely on COAs for consistent, repeatable experiments.
Most Canadian suppliers use:
Delivery times:
📦 1–2 business days Canada-wide.
Domestic shipping provides:
Permitted scientific applications include:
✔ in-vitro mitochondrial studies
✔ oxidative stress modelling
✔ cellular bioenergetic experiments
✔ biochemical signalling assays
✔ molecular pathway analysis
✔ structural lipid research
Not permitted:
❌ human use
❌ animal use
❌ therapeutic suggestions
❌ dosing instructions
❌ medical claims
All SS-31 usage in Canada must follow research-use-only rules.
Canadian researchers avoid suppliers who:
Transparency is a core requirement in Canadian research.
Benefits include:
Domestic sourcing avoids U.S. customs and temperature fluctuations.
Yes — strictly for in-vitro, laboratory, and scientific research.
No. It requires a legitimate research purpose, not medical authorization.
No. It is not approved as a therapeutic product.
Canadian labs typically use ≥99% laboratory purity.
Most domestic shipments arrive in 1–2 business days.
[3] Elamipretide Improves Mitochondrial Function in the Failing Human Heart. J. Am. Heart Assoc. (2019).
All information is provided for scientific and laboratory reference only.
SS-31 is intended strictly for research, laboratory, and in-vitro use, not for human or animal use.
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