High-Purity NAD+ Now at Promotional Pricing
High-Purity NAD+ Now at Promotional Pricing
GHK-Cu (Glycyl-L-Histidyl-L-Lysine-Copper) is one of the most widely researched copper-binding peptides in Canada due to its unique tripeptide structure and powerful effects on cellular and molecular pathways [1]. As research interest continues to grow through 2025 and 2026, laboratories across Canada require high-purity, research-grade GHK-Cu for their controlled scientific environments.
GHK-Cu is not just a peptide; it is a signaling molecule that regulates the expression of a vast number of human genes, making it a critical tool for studies in tissue repair, antioxidant mechanisms, and anti-inflammatory pathway analysis [2].
This guide details the precise molecular role of GHK-Cu and the high purity standards expected by Canadian researchers.
GHK-Cu is a naturally occurring tripeptide (Glycine-Histidine-Lysine) that has an extremely high affinity for copper (Cu²⁺) ions, with which it forms a stable complex [3]. GHK levels naturally decline with age, coinciding with a noticeable decrease in the regenerative capacity of an organism [4].
Key Research Relevance:
Copper Transport: GHK acts as a carrier, facilitating the stable, non-toxic transport of copper ions into cells, which is vital for the function of numerous antioxidant enzymes like Superoxide Dismutase (SOD) [3].
Gene Modulation: Studies using advanced mapping techniques (like the Broad Institute’s Connectivity Map) show GHK-Cu can up- and down-regulate over 4,000 human genes, effectively shifting gene expression from a pathological state back toward a healthier one [2, 5].
In controlled in-vitro studies, GHK-Cu is primarily investigated for its tri-fold mechanistic actions:
GHK-Cu is critical for regulating the synthesis and breakdown of the ECM, the structural scaffolding around cells.
It stimulates fibroblasts to increase the production of collagen (Type I and III), elastin, and glycosaminoglycans [3, 6].
It modulates the activity of matrix metalloproteinases (MMPs)—enzymes that break down proteins—helping to regulate tissue remodeling and prevent excessive degradation [6].
GHK-Cu is studied for its potent cell-protective properties:
Antioxidant Effects: It blocks the formation of reactive oxygen species (ROS) and is shown to increase the activity of antioxidant enzymes [7].
Cytokine Modulation: It has been shown to suppress the expression of pro-inflammatory cytokines, suggesting a role in reducing chronic inflammation models [1].
GHK-Cu has been observed to influence cellular behavior:
It promotes the proliferation and migration of cells essential for tissue repair, such as fibroblasts and keratinocytes [4].
It has been shown to increase markers associated with stemness (like integrins and p63) in epidermal basal cells, indicating a potential role in enhancing regenerative capacity [7].
Canadian laboratories generally require:
High-purity materials ensure more consistent laboratory outcomes.
In Canada, GHK-Cu is handled under research-use-only (RUO) classification. This means:
All information here respects Canada’s research-only guidelines.
Pricing varies depending on:
Typical price ranges in Canada:
| GHK-Cu Type | Price |
|---|---|
| Standard research grade | $69–$89 |
| High-purity analytical grade | $79–$129 |
Domestic suppliers often offer faster delivery, better stability, and more consistent documentation.
Canadian researchers typically prefer domestic suppliers because:
Laboratories benefit from consistent delivery windows and proper handling during shipping.
Canadian researchers look for suppliers who provide:
For a broader overview of peptides available in Canada, see:
👉 Peptides in Canada — 2025–2026 Guide
(/peptides-canada/)
All materials described here are strictly for scientific, laboratory, and in-vitro use only, not for human or animal consumption.
Content is provided for informational purposes for researchers.
Join our list and get an instant 10% discount code — valid for first-time buyers.
